Our comment primarily concerns the Department of Energy’s (DOE) use of the social cost of carbon (SCC) in the cost/benefit analysis of the Energy Conservation Program: Energy Conservation Standards for Compressors proposed rulemaking. The DOE’s determination of the SCC is discordant with the best scientific literature on the equilibrium climate sensitivity and the fertilization effect of carbon dioxide—two critically important parameters for establishing the net externality of carbon dioxide emissions. It is also at odds with existing Office of Management and Budget (OMB) guidelines for preparing regulatory analyses. It is based upon the output of Integrated Assessment Models (IAMs) which have little utility because of their great uncertainties. They provide no reliable guidance as to the sign, much less the magnitude of the social cost of carbon. Additionally, as run by the Interagency Working Group (IWG) (whose results were incorporated by the DOE in this action), the IAMs produce illogical results that indicate a misleading disconnection between climate changes and the SCC value. Further, we show that the sea level rise projections (and thus SCC) of at least one of the IAMs (DICE 2010) is not supported by the mainstream climate science.