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Winter 2016/2017

Vol. 39 No. 4
From the Cover
Features

Beyond the Low‐​Hanging Fruit

By Craig Loehle and Erik B. Schilling

How should policymakers judge environmental regulations when marginal costs are rising and marginal benefits are falling?

The FDA’s Dr. No’s

By John J. Cohrssen and Henry I. Miller

The agency’s fear of Type II errors inhibits drug development and harms patients

For the Record
Final Word